李孟娟

李孟娟 教授 (Lee, Mon-Juan)
3212、3350  
mjlee@mail.cjcu.edu.tw  
第二教學大樓 7F (Second Academic Building) T20716室  
  •  本學期授課
  •  課表&接見時間
  •  歷年授課資訊
  • https://d908205.wixsite.com/mjlee
  • (06) 2785010  
    Lab 第二教學大樓(Second Academic Building) T20108室  
    VCard
    ORCID https://orcid.org/0000-0003-0420-6244

     專長 Specialties
    專長 Specialties
    幹細胞再生醫學 Stem cells and regenerative medicine
    奈米生醫材料 Nanobiomaterials
    基因治療 Gene therapy
    液晶生物感測 Liquid crystal-based biosensing

    學歷 Educational Background
    畢/肄業學校
    School of graduation / non-completion
    主修學門系所
    Department of major
    學位
    Degree
    起迄年月
    Period
    國立清華大學 生命科學系 博士 2001/09 ~ 2006/07
    國立清華大學 化學工程研究所 碩士 1998/07 ~ 2000/06
    國立清華大學 化學工程學系 學士 1994/09 ~ 1998/06

     本校經歷 Experience at CJCU
    服務單位
    Service Unit
    職稱
    Position
    起迄年月
    Period
    生物科技學系 教授 2019/02 ~ 迄今
    醫藥科學產業學系 合聘教師 2019/02 ~ 迄今
    醫藥科學產業學士學位學程 主任 2018/10 ~ 迄今
    醫藥科學產業學系 主任 2018/10 ~ 迄今
    醫學社會暨健康照護學士學位學程 主任 2018/10 ~ 2019/01
    醫藥照護產業進修學士學位學程 主任 2018/10 ~ 2019/01
    醫學研究所 合聘教師 2014/08 ~ 2019/01
    醫藥創新研究中心 研究員 2014/08 ~ 2019/01
    生物科技學系 副教授 2014/02 ~ 2019/01
    生物科技學系 助理教授 2008/08 ~ 2014/01

     外校經歷 Other School Experience
    服務學校
    Service School
    服務單位
    Service Unit
    職稱
    Position
    起迄年月
    Period
    Biosensors (ISSN 2079-6374) The special issue "Electrical and Electro-Optical Biosensors for Protein Detection" Guest Editor 2020/04 ~ 2021/09
    Georgetown University Lombardi Comprehensive Cancer Center Visiting Scholar 2018/02 ~ 2018/07
    國立成功大學 醫學工程研究所 博士後研究員 2007/07 ~ 2008/07
    高雄醫學大學 醫學研究所 博士後研究員 2006/08 ~ 2007/06
    Georgetown University Lombardi Cancer Center Internship 2003/07 ~ 2003/10
    台灣神隆股份有限公司 研發部 助理研究員 2000/08 ~ 2001/07

     國外期刊論文 Papers in foreign journals
    Y.-Q. Wang, P.-C. Wu, M.-J. Lee,* and W. Lee*, 'Photocontrolled capacitive biosensor based on photoresponsive azobenzene-doped liquid crystals for label-free protein assay,' J. Mol. Liq., 345, Jan. 2022, 117908. (SCI,SCIE ) [107-2112-M-009-012- MY3, 109-2320-B-309-001, 110-2112-M-A49-023, and 110-2320- B-309-001]
    P.-C. Wu, C.-P. Pai, M.-J. Lee,* and W. Lee*, 'A single-substrate biosensor with spin-coated liquid crystal film for simple, sensitive and label-free protein detection,' Biosensors, 11, Oct. 2021, 374. (SCI,SCIE ) [107-2112-M-009-012-MY3, 109-2320-B-309-001, 110-2112-M-A49-023, and 110-2320- B-309-001]
    C.-H. Cheng, M.-Y. Shie, Y.-H. Lai, N.-P. Foo, M.-J. Lee,* and C.-H. Yao* , 'Fabrication of 3D printed poly (lactic acid)/polycaprolactone scaffolds using TGF-β1 for promoting bone regeneration,' Polymers, 13, Oct. 2021, 3731. (SCI,SCIE ) [ANHRF110‐04]
    H. Shaban, M.-J. Lee,* and W. Lee*, 'Label-free detection and spectrometrically quantitative analysis of the cancer biomarker CA125 based on lyotropic chromonic liquid crystal,' Biosensors, 11, Aug. 2021, 271. (SCI,SCIE ) [109-2320-B-309-001; 110-2320-B-309-001]
    C.-C. Lee,# C.-M. Hung,# C.-H. Chen, Y.-C. Hsu, Y.-P. Huang, T.-B. Huang, and M.-J. Lee* (#The authors contributed equally to this work), 'Novel aptamer-based small-molecule drug screening assay to identify potential sclerostin inhibitors against osteoporosis,' Int. J. Mol. Sci., 22, Aug. 2021, 8320. (SCI,SCIE ) [105-2633-B-309-001 and 106-2633-B-309-001]
    R. B. Barndt, M.-J. Lee, N. Huang, D. D. Lu, S.-C. Lee, P.-W. Du, C.-C. Chang, P.-F. B. Tsai, Y.-S. K. Huang, H.-M. Chang, J.-K. Wang, C.-H. Lai, M. D. Johnson, C.-Y. Lin, 'Targeted HAI-2 deletion causes excessive proteolysis with prolonged active prostasin and depletion of HAI-1 monomer in intestinal but not epidermal epithelial cells,' Human Molecular Genetics, Jun. 2021, ddab150. (SCI,SCIE )
    M.-J. Lee, C.-P. Pai, P.-C. Wu, and W. Lee, 'Label-free single-substrate quantitative protein assay based on optical characteristics of cholesteric liquid crystals,' J. Mol. Liq., 331, Jun. 2021, 115756. (SCI,SCIE ) [109-2320-B-309-001]
    H. Shaban, S.-C. Yen, M.-J. Lee, and W. Lee, 'Signal amplification in an optical and dielectric biosensor employing liquid crystal-photopolymer composite as the sensing medium,' Biosensors, 11, 3, Mar. 2021, 81. (SCI,SCIE ) [109-2320-B-309-001]
    Yang, C.-D.; Chuang, S.-C.; Cheng, T.-L.; Lee, M.-J.; Chen, H.-T.; Lin, S.-Y.; Huang, H.-T.; Ho, C.-J.; Lin, Y.-S.; Kang, L.; Ho, M.-L.; Chang, J.-K.; Chen, C.-H., 'An Intermediate Concentration of Calcium with Antioxidant Supplement in Culture Medium Enhances Proliferation and Decreases the Aging of Bone Marrow Mesenchymal Stem Cells,' Int. J. Mol. Sci., 22, Feb. 2021, 2095. (SCI,SCIE )
    L. B. B. Aquino, M. Y. U. Barbaza, J. L. T. Ramos, M.-J. Lee, S.-Y. Ko, C.-L. Hsieh, K. A. De Castro-Cruz,* and P.-W. Tsai*, 'Aerial parts of Euphorbia hirta L. in polar and non-polar solvents: phytochemical, antioxidant and glucose uptake studies for potential source of adjunct drug for diabetes,' Trop. J. Nat. Prod. Res., 4, Nov. 2020, 708–713.
    M.-J. Lee,* F.-F. Duan, P.-C. Wu, and W. Lee*, 'Liquid crystal–photopolymer composite films for label-free single-substrate protein quantitation and immunoassay,' Biomed. Opt. Express, 11, 9, Sep. 2020, 4915-4927. (SCI,SCIE ) [109-2320-B-309-001]
    B. Jia, H.A. Thompson, R.B. Barndt, Y.-L. Chiu, M.-J. Lee, S.-C. Lee, J.-K. Wang, H.-J. Tang,* C.-Y. Lin,* and M.D. Johnson*, 'Mild acidity likely accelerates the physiological matriptase autoactivation process: a comparative study between spontaneous and acid-induced matriptase zymogen activation,' Human Cell, Aug. 2020, https://doi.org/10.1007/s13577-020-00410-1. (SCI,SCIE )
    M.-J. Lee* and W. Lee*, 'Liquid crystal-based capacitive, electro-optical and dielectric biosensors for protein quantitation,' Liq. Cryst., 47, Aug. 2020, 1145–1153. (SCI,SCIE ) [106-2314-B-309-001]
    W.-L. Hsu, M.-J. Lee* and W. Lee* , 'Electric-field-assisted signal amplification for label-free liquid-crystal-based detection of biomolecules,' Biomed. Opt. Express, 10, 10, Oct. 2019, 4987–4998. (SCIE ) [106-2314-B-309-001, 107-2112-M-009-012-MY3]
    Lin, C.-M., P.-C. Wu, M.-J. Lee* and W. Lee* , 'Label-free protein quantitation by dielectric spectroscopy of dual-frequency liquid crystal,' Sens Actuator B-Chem, 282, Mar. 2019, 158–163. (SCIE ) [106-2314-B-309-001]
    Lin, S. Y., L. Kang, C. Z. Wang, H. H. Huang, T. L. Cheng, H. T. Huang, M. J. Lee, Y. S. Lin, M. L. Ho, G. J. Wang and C. H. Chen*, '(−)-Epigallocatechin-3-gallate (EGCG) enhances osteogenic differentiation of human bone marrow mesenchymal stem cells,' Molecules, 23, Dec. 2018, 3221. (SCIE ) [104-2314-B-037-032-MY3]
    Chiang, Y.-L., M.-J. Lee* and W. Lee.*, 'Enhancing detection sensitivity in quantitative protein detection based on dye-doped liquid crystals,' Dyes Pigments , 157, Oct. 2018, pp. 117–122. (SCIE ) [106-2923-M-009-002-MY3]
    Lee, M.-J.,* Y.-L. Chiang, A. Karn, P.-C. Wu and W. Lee*, 'Dye- and dye-doped liquid crystals in biosensing,' Proc. SPIE, 10735, Liquid Crystals XXII, Sep. 2018, 1073509. (EI Compendex ) [106-2314-B-309-001]
    S. Y. Lin, L. Kang, J. C. Chen, C. Z. Wang, H. H. Huang, M. J. Lee, T. L. Cheng, C. F. Chang, Y. S. Lin, and C. H. Chen, '(-)-Epigallocatechin-3-gallate (EGCG) enhances healing of femoral bone defect,' Phytomedicine, In press, Jul. 2018 . (SCIE )
    Wu, P.-C., A. Karnb, M.-J. Lee*, W. Lee* and C.-Y. Chen, 'Dye-liquid-crystal-based biosensing for quantitative protein assay,' Dyes Pigments, 150, Mar. 2018, pp. 73–78. (SCIE ) [105-2633-B-309-001]
    M. J. Lee,* C. H. Chang and W. Lee*, 'Label-free protein sensing by employing blue phase liquid crystal,' Biomed. Opt. Express, 8, 3, Mar. 2017, 1712–1720. (SCIE ) [103-2633-B-309-001]
    Hung, C. M., Y. C. Hsu, T. Y. Chen, C. C. Chang and M. J. Lee*, 'Cyclophosphamide promotes breast cancer cell migration through CXCR4 and matrix metalloproteinases,' Cell Biol. Int., 41, 3, Mar. 2017, 345–352. (SCI ) [MOST 101-2314-B- 309-001-MY3]
    Huang, Y. P., C. M. Hung, Y. C. Hsu, C. Y. Zhong, W. R. Wang, C. C. Chang and M. J. Lee*, 'Suppression of breast cancer cell migration by small interfering RNA delivered by polyethylenimine-functionalized graphene oxide,' Nanoscale Res. Lett., 11, Dec. 2016, 247. (SCIE ) [MOST 103-2633-B-309-001]
    M.-J. Lee*, Y.-C. Sung, Y.-C. Hsiao, and W. Lee* , 'Chiral liquid crystals as biosensing platforms,' Proceedings of SPIE (Society of Photo-Optical Instrumentation Engineers), Liquid Crystals XX (Conference 9940), 9940-19, Sep. 2016, 99400K-1–6. (EI )
    Chi-Hao Lin, Mon-Juan Lee, and Wei Lee, 'Bovine serum albumin detection and quantitation based on capacitance measurements of liquid crystals,' Appl. Phys. Lett., 109, 9, Aug. 2016, 093703. (SCIE ) [MOST 103-2633-B-309-001]
    Hsiao, Y. C., Y. C. Sung, M. J. Lee* and W. Lee*, 'Highly sensitive color-indicating and quantitative biosensor based on cholesteric liquid crystal,' Biomed. Opt. Express, 6, Dec. 2015, 5033-5038. (SCI ) [MOST 103-2633-B-309-001]
    Lee, M. J.*, C. H. Lin, and W. Lee*, 'Liquid-crystal-based biosensing beyond texture observations. ,' Proc. SPIE , 9565, Liquid Crystals XIX, Sep. 2015, 956510. (EI ) [MOST 101-2314-B-309-001-MY3]
    Yo-Hsian Tsai, Kuan-Lian Lin, Yuan-Pin Huang, Yi-Chiang Hsu, Chung-Hwan Chen, Yuhsin Chen, Min-Hua Sie, Gwo-Jaw Wang, Mon-Juan Lee, 'Suppression of ornithine decarboxylase promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells,' FEBS Letters, 589, 16, Jul. 2015, 2058–2065. (SCI ) [101-2314-B-309-001-MY3]
    Hui-Wen Su, Mon-Juan Lee, Wei Lee, 'Surface modification of alignment layer by ultraviolet irradiation to dramatically improve the detection limit of liquid-crystal-based immunoassay for the cancer biomarker CA125,' Journal of Biomedical Optics, 20, 5, May. 2015, 057004. (SCI ) [101-2314-B-309-001-MY3]
    Sun, S.-H., M.-J. Lee*, Y.-H. Lee, W. Lee*, X. Song and C.-Y. Chen, 'Mesogen of large birefringence enhances the sensitivity of liquid-crystal-based immunoassays for the cancer biomarker CA125,' Biomed. Opt. Express , 6, Jan. 2015, 245-256. (SCI ) [101-2314-B-309-001-MY3]
    Lee, M. J., H. W. Su, S. H. Sun, and W. Lee*, 'Ultrahigh sensitivity in liquid-crystal-based immunodetection by surface modification of the alignment layer,' Proc. SPIE, 9182, Liquid Crystals XVIII, Oct. 2014 . (EI ) [101-2314-B-309-001-MY3]
    Hui-Wen Su,Yun-Han Lee, Mon-Juan Lee,Yi-Chiang Hsu, and Wei Lee, 'Label-free immunodetection of the cancer biomarker CA125 using high-∆n liquid crystals ,' J. Biomed. Opt., 19, 7, Jul. 2014, 077006-1–6. (SCI ) [101-2314-B-309-001-MY3]
    3. Tsai, Y. J.#, M. J. Lee#, M. D. T. Chang* and H. Huang*. (#The authors contributed equally to this work)., 'The effect of catalase on migration and invasion of lung cancer cells by regulating the activities of cathepsin S, L, and K,' Exp. Cell Res., 323, 1, Apr. 2014, 28-40 . (SCI ) [NSC95-2311-B-007-013]
    Lee, M. J.*, Y. Chen, Y. P. Huang, Y. C. Hsu, L. H. Chiang and G. J. Wang, 'Exogenous polyamines promote osteogenic differentiation by reciprocally regulating osteogenic and adipogenic gene expression,' J. Cell Biochem. , 114, Dec. 2013, 2718-2728. (SCI ) [NSC101-2314-B-309-001-MY3]
    Tsai, Y. J., M. J. Lee, M. D. T. Chang*, H. C. Wang, C. C. Lin and H. Huang*. , 'Effects of novel human cathepsin S inhibitors on cell migration in human cancer cells,' Journal of Enzyme Inhibition and Medicinal Chemistry , Oct. 2013 . (SCI )
    Lee, M. J.#, H. T. Chen#, S. C. Chuang, C. H. Chen, M. L. Ho, Y. C. Fu, C. M. Huang, G. J. Wang, L. Kang, J. K. Chang, 'PPARgamma silencing enhances osteogenic differentiation of human adipose-derived mesenchymal stem cells,' J. Cell Mol. Med., 17, 9, Sep. 2013, 1188-1193. (SCI ) [98-EC-17-A-17-S1-041]
    C. C. Chang, C. M. Hung, Y. R. Yang, M. J. Lee and Y. C. Hsu*, 'Sulforaphane induced cell cycle arrest in the G2/M phase via the blockade of cyclin B1/CDC2 in human ovarian cancer cells,' J. Ovarian Res., 6, Jul. 2013, 41. (SCI ) [EDAHP-100018]
    Huang, Y. P., I. J. Lin, C. C. Chen, Y. C. Hsu, C. C. Chang and M. J. Lee*, 'Delivery of small interfering RNAs in cervical cancer cells by polyethyleneimine-functionalized carbon nanotubes,' Nanoscale Res. Lett., 8, Jun. 2013, 267. (SCI ) [NSC101-2314-B-309-001-MY3]
    Lee, M. J., Y. T. Yang, V. Lin, and H. Huang, 'Site-directed mutations of the gatekeeping loop region affect the activity of Escherichia coli spermidine synthase,' Mol. Biotechnol., 54, 2, Jun. 2013, 572-580. (SCI ) [NSC93-3112-B-007-016 and NSC92-3112-B-007-015]
    Chen, H. T.#, M. J. Lee#, M. L. Ho, C. H. Chen, S. H. Hung, H. I. Wang, Y. C. Fu, Y. H. Wang, G. J. Wang, and J. K. Chang (#The authors contributed equally to this work.), 'Proliferation and differentiation potential of human adipose-derived mesenchymal stem cells isolated from elderly patients with osteoporotic fractures,' J. Cell Mol. Med. , 16, 3, Mar. 2012, 582-593. (SCI ) [96-EC-17-A-17-S1-041]
    Lee, M. J., Liu, C. L., and H. Huang, 'Identification and biochemical characterization of a unique Mn2+-dependent UMP kinase from Helicobacter pylori,' Arch. Microbiol., 192, Jul. 2010, 739-746. (SCI ) [NSC 95-2311-B-007-013]
    Huang, Y. P., M. J. Lee, M. K. Yang, and C. W. Chen, 'The effects of montmorillonite-clay alignment on the crystallization and ion-conducting behaviors of poly(ethylene oxide)-nanocomposites,' Appl. Clay Sci. , 49, May. 2010, 163-169. (SCI ) [NSC 96-2221-E-230-009]
    Ho, M. L., Y. H. Chen, H. J. Liao, C. H. Chen, S. H. Hung, M. J. Lee, G. J. Wang, J. K. Chang, 'Simvastatin increases osteoblasts and osteogenic proteins in ovariectomized rats,' Eur. J. Clin. Invest. , 39, 4, Apr. 2009, 296-303. (SCI ) [NSC 93-2314-B-037-053]
    Lee, M. J., H. Huang, W. Lin, R. R. Yang, C. L. Liu, and C. Y. Huang, 'Activation of Helicobacter pylori inorganic pyrophosphatase and the importance of Cys16 in thermostability, enzyme activation and quaternary structure,' Arch. Microbiol. , 188, Jun. 2007, 473-482. (SCI ) [NSC 93-3112-B-007-016]
    Lee, M. J., C. H. Liu, S. Y. Wang, C. T. Huang, and H. Huang, 'Characterization of the Soj/Spo0J chromosome segregation proteins and identification of putative parS sequences in Helicobacter pylori,' Biochem. Biophys. Res. Commun. , 342, Feb. 2006, 744-50. (SCI ) [NSC 92-3112-B-007-015]
    Lee, M. J., C. Y. Huang, Y. J. Sun, and H. Huang, 'Cloning and characterization of spermidine synthase and its implication in polyamine biosynthesis in Helicobacter pylori strain 26695,' Protein Expr. Purif. , 43, May. 2005, 140-8. (SCI ) [NSC 91-3112-B-007-014]
    Lu, P. K., S. Y. Chien, J. Y. Tsai, C. T. Fong, M. J. Lee, H. Huang, and Y. J. Sun, 'Crystallization and preliminary X-ray diffraction analysis of spermidine synthase from Helicobacter pylori,' Acta Crystallogr. D Biol. Crystallogr. , 60, Nov. 2004, 2067-9. (SCI ) [NSC 93-3112-B-007-014]
    Hung, R. J., I. W. J. Hsu, J. L. Dreiling, M. J. Lee, C. A. Williams, M. D. Oberst, R. B. Dickson, and C. Y. Lin, 'Assembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation at mammary epithelial cell-cell contacts,' Am. J. Physiol. Cell Physiol. , 286, May. 2004, C1159-69. (SCI )


     國外會議論文 Papers in overseas conferences
    H. Shaban, M.-J. Lee* and W. Lee* ,'Optical detection of bovine serum albumin by lyotropic liquid crystal', 2020 OSA Frontiers in Optics + Laser Science APS/DLS Conference (FiO+LS) , Sep. 2020 ,Technical Conference & Virtual Exhibits.
    W.-L. Hsu, M.-J. Lee,* and W. Lee* ,'Signal Amplification for biodetection in field-assisted optical sensing', Optics & Photonics Taiwan, International Conference 2019 (OPTIC 2019) , Dec. 2019 ,Taichung, Taiwan.
    S.-C. Yen, P.-C. Wu, M.-J. Lee,* and W. Lee* ,'Enhancement of the limit of protein detection based on polymer-stabilized liquid crystals', Optics & Photonics Taiwan, International Conference 2019 (OPTIC 2019) , Dec. 2019 ,Taichung, Taiwan.
    W.-L. Hsu, M.-J. Lee*, and W. Lee* ,'Electric field-assisted signal amplification for liquid crystal-based protein detection', 18th Optics of Liquid Crystals Conference (OLC 2019) , Sep. 2019 ,Québec, Canada.
    M.-J. Lee* and W. Lee* ,'Exploiting the electrical and optical properties of liquid crystals in biosensing and quantitative bioassays', The 14th Asian Congress on Biotechnology (ACB2019) , Jul. 2019 ,Taipei, Taiwan.
    W.-L. Hsu, P.-C. Wu, M.-J. Lee* and W. Lee* ,'DNA biosensing based on an unsandwiched liquid crystal', 4th Asian Conference on Liquid Crystals (ACLC 2019) , Jan. 2019 ,Shenzhen, China.
    F.-F. Duan, P.-C. Wu, M.-J Lee* and W. Lee* ,'Immunoassay of the cancer biomarker CA125 using a liquid-crystal-coated substrate', 4th Asian Conference on Liquid Crystals (ACLC 2019) , Jan. 2019 ,Shenzhen, China.
    W.-L. Hsu, C.-P. Pai, P.-C. Wu, M.-J. Lee* and W. Lee* ,'Label-free biodetection based on a liquid crystal film coated on a single substrate', Optics & Photonics Taiwan, International Conference 2018 (OPTIC 2018) , Dec. 2018 ,Tainan, Taiwan. [MOST 106-2314-B-309-001]
    C.-M. Lin, P.-C. Wu, W.-K. Wu, M.-J. Lee* and W. Lee* ,'Dielectric spectroscopy-based label-free protein quantitation using dual-frequency liquid crystal', Optics & Photonics Taiwan, International Conference 2018 (OPTIC 2018) , Dec. 2018 ,Tainan, Taiwan.
    W.-L. Hsu, C.-P. Pai, P.-C. Wu, M.-J. Lee* and W. Lee* ,'Biomolecule detection based on a liquid crystal film coated on a single substrate', 2018 OSA Frontiers in Optics + Laser Science APS/DLS Conference (FiO+LS) , Sep. 2018 ,Washington, DC, USA.
    M.-J. Lee and W. Lee* ,'Optical, capacitance and dielectric methods for liquid-crystal-based biosensing', 22nd International Symposium on Advanced Display Materials and Devices (ADMD 2018) , Jul. 2018 , pp. 47 ,Jeju, South Korea. [106-2923-M-009-002-MY3]
    C.-M. Lin, P.-C. Wu, M.-J. Lee,* and Wei Lee* ,'Label-free protein quantitation by means of dielectric spectroscopy with dual-frequency liquid crystal', 28th Anniversary World Congress on Biosensors (Biosensors 2018) , Jun. 2018 , pp. 2.127 ,Miami, USA. [106-2314-B-309-001]
    Y.-L. Chiang, M.-J. Lee,* and Wei Lee* ,'High-sensitivity biosensing for protein detection using dye-doped liquid crystals and polarized light', 28th Anniversary World Congress on Biosensors (Biosensors 2018) , Jun. 2018 , pp. 3.032 ,Miami, USA. [106-2314-B-309-001]
    M.-J. Lee, H.-W. Su, S.-H. Sun, A. Karn, Y.-C. Hsiao, C.-H. Chang, C.-H. Lin, C.-M. Lin, P.-C. Wu, and Wei Lee* ,'Optical, capacitance and dielectric methods for liquid-crystal-based biosensing', The 7th international symposium on liquid crystal photonics (SLCP 2018) , Apr. 2018 ,Changshu, Jiangsu, China.
    M. J. Lee*, Y. P. Huang, and C. C. Chen ,'Potential bone-stimulating sclerostin inhibitors screened from an aptamer-based competitive assay', 10th World Congress and Expo on Cell & Stem Cell Research , Mar. 2018 ,New York, USA. [106-2633-B-309-001]
    Y.-L. Chiang, M.-J. Lee, and W. Lee* National Sun Yat-sen University, , December 7–9, 2017. ,'Protein quantitation based on optical absorption of dye-doped liquid crystal', OPTIC 2017 , Dec. 2017 , pp. 2 ,Kaohsiung, Taiwan. [106-2314-B-309-001]
    C.-M. Lin, P.-C. Wu, M.-J. Lee, and W. Lee* on Internet, 2 p, , December 7–9, 2017. ,'Protein detection and quantitation based on dielectric responses of dual-frequency liquid crystal', OPTIC 2017 , Dec. 2017 , pp. 2 ,Kaohsiung, Taiwan. [106-2314-B-309-001]
    Lee, M. J.* and Y. P. Huang ,'An aptamer-based screening assay for potential drug candidates against osteoporosis', Aptamers 2017 , Apr. 2017 ,Oxford. [MOST 105-2633-B-309-001]
    Chang, C.H., C. M. Lin, M. J. Lee, K. H. Yang, and W. Lee* ,'Applications of blue-phase liquid crystals for biodetection and quantitation', 3rd Asian Conference on Liquid Crystals (ACLC 2017) , Feb. 2017 ,Tainan, Taiwan.
    Lin, C. H., Y. L. Chiang, M. J. Lee, and W. Lee* ,'Quantitative biosensing methods based on measurements of phase retardation and capacitance of liquid-crystal cells', 3rd Asian Conference on Liquid Crystals (ACLC 2017) , Feb. 2017 ,Tainan, Taiwan.
    Hsiao, Y. C., Y. C. Sung, M.-J. Lee* and W. Lee.* ,'A highly sensitive and color-indicating protein assay method based on cholesteric liquid crystals', 26th Anniversary World Congress on Biosensors (Biosensors 2016) , May. 2016 ,Gothenburg, Sweden.
    Chang C. H., Y. C. Hsiao, M.-J. Lee* and W. Lee* ,'Label-free protein sensor by using blue phase liquid crystal', 26th Anniversary World Congress on Biosensors (Biosensors 2016) , May. 2016 ,Gothenburg, Sweden.
    Sung, Y. C., Y. C. Hsiao, M. J. Lee* and W. Lee* ,'Sensitive Biosensor Based on Cholesteric Mesophase', 3rd Annual International Conference on Optoelectronics, Photonics & Applied Physics , Jan. 2016 ,. [MOST 103-2633-B-309-001]
    Huang, Y. P., W. R. Wang, C. Y. Zhong and M. J. Lee.* ,'Gene delivery by polyethylenimine-functionalized graphene oxide suppresses breast cancer cell migration', 250th ACS National Meeting & Exposition , Aug. 2015 ,Boston, MA, . [MOST 103-2633-B-309-001]
    Lin, C. H., M. J. Lee* and W. Lee* ,'Liquid crystal electro-optical devices for biosensing: detection of bovine serum albumin as an example', 8th International Symposium on Photonics and Optoelectronics , Aug. 2015 ,Shanghai. [MOST 101-2314-B-309-001-MY3]
    Lee, M. J.*, M. H. Sie, S. Y. Lin, C. H. Chen and G. J. Wang ,'Suppression of polyamine biosynthesis promotes osteogenic differentiation of mesenchymal stem cells and stimulates bone formation in ovariectomized rat model', ISSCR 13th Annual Meeting , Jun. 2015 ,Stockholm. [MOST 101-2314-B-309-001-MY3]
    Sun, S.-H., M.-J. Lee, Y.-H. Lee, and W. Lee* ,'High-birefringence liquid crystal for improved sensitivity and reliability in liquid crystal-based immunoassay of the cancer biomarker CA125', 25th International Liquid Crystal Conference (ILCC 2014) , Jun. 2014 , pp. 1.086 ,Trinity College, Dublin, Ireland.
    Su, H. W., M. J. Lee* and W. Lee* ,'Ultrahigh sensitivity in liquid-crystal-based immunodetection using a modified sample-preparation technique', Biosensors 2014 , May. 2014 ,Melbourne, Australia.
    Lee, M. J.*, K. L. Lin, Y. S. Tsai, Y. P. Huang and G. J. Wang ,'Exogenous polyamines promote osteogenic differentiation in human osteoblasts', 60th Annual Meeting of the Orthopaedic Research Society , Mar. 2014 ,New Orleans, LA, USA. [NSC101-2314-B-309-001-MY3]
    Lee, M. J.*, Y. S. Tsai, K. L. Lin ,'Suppression of polyamine biosynthesis promote osteogenic differentiation of human bone marrow-derived mesenchymal stem cells', 11th ISSCR Annual Meeting , Jun. 2013 ,Boston, MA, USA. [NSC101-2314-B-309-001-MY3]
    Su, H. W., M. J. Lee, and W. Lee. ,'Label-free immunodetection of cancer biomarker CA125 using high-delta n liquid crystals', Optics & Photonics Taiwan, International Conference 2013 (OPTIC 2013) , Dec. 2013 , pp. 50 ,Chungli, Taiwan. [NSC101-2314-B-309-001-MY3]
    Lee, M. J.*, Y. P. Huang, J. R. Hsu, C. Y. Chen ,'Polyamines promote osteogenic differentiation of human bone marrow-derived mesenchymal stem cells', Ninth ISSCR Annual Meeting , Jun. 2011 ,Toronto, Ontario, Canada.
    Lee, M. J., Y. P. Huang, M. K. Yang, C. W. Chen, and C. H. Lin ,'Crystallization and ion-conducting behaviors of poly(ethylene oxide)-nanocomposite under an electric field', 38th ACS National Meeting & Exposition , Aug. 2009 ,Washington DC, USA.
    Wang, Y. H., M. J. Lee, J. K. Chang, M. L. Ho, H. C. Chu, S. C. Lai, and G. J. Wang ,'Transfection of human bone marrow stromal cells using microporation, an effective non-viral transfection technique', 55th Annual Meeting of the Orthopaedic Research Society , Feb. 2009 ,Las Vegas, Nevada, USA.
    Lee, M. J., C. M. Huang, H. T. Chen, G. J. Wang, M. L. Ho, and J. K. Chang ,'Suppression of PPARγ induces osteogenic gene expression and differentiation of adipose tissue-derived stem cells', 55th Annual Meeting of the Orthopaedic Research Society , Feb. 2009 ,Las Vegas, Nevada, USA.
    Lee, M. J., Y. P. Huang, P. H. Huang, and C. H. Lin ,'Ion-conducting behavior of gel electrolyte nanocomposite prepared by photopolymer-encapsulated ionic liquid comprising montmorillonite clay', European Polymer Congress , Jul. 2009 ,Graz.
    Chen, H. T., M. L. Ho, M. J. Lee, C. H. Chen, H. I. Wang, Y. H. Chen, G. J. Wang, J. K. Chang ,'Osteogenic potential of human adipose tissue-derived stem cells in the elderly osteoporotic population', Sixth ISSCR Annual Meeting , Jun. 2008 ,Philadelphia, USA.
    Lee, M. J., H. Huang, C. K. Chou, Y. C. Tsai, F. G. Tseng, and C. C. Chieng ,'Diagnostic antigens and antibodies patterned by micro stamping system', Sixth International Conference on Miniaturized Chemical and Biochemical Analysis Systems , Nov. 2002 ,Nara New Public Hall, Nara, Japan.

     國內會議論文 Papers in domestic conferences
    S.-C. Yen, Y.-Y. Tseng, M.-J. Lee* and W. Lee* ,'Nematic–polymer integrated cell platforms for biosensing', 2020 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2020 ,Tainan, Taiwan.
    B.-S. Chen, P.-C. Wu, M.-J. Lee* and W. Lee* ,'Characteristics of a label-free biosensor by using cationic surfactant-doped liquid crystal', 2020 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2020 ,Tainan, Taiwan.
    Y.-Q. Wang, P.-C. Wu, M.-J. Lee* and W. Lee* ,'Label-free biosensing by using photo-responsive azo-chiral-doped-liquid-crystal', 2020 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2020 ,Tainan, Taiwan.
    H. Shaban, M.-J. Lee* and W. Lee* ,'Spectrometric measurement of optical signal for label-free and lyotropic-liquid-crystal-based biosensing', 2020 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2020 ,Tainan, Taiwan.
    W.-L. Hsu, H. Shaban, M.-J. Lee* and W. Lee* ,'Electrically enhanced optical signal for label-free and liquid-crystal-based biosensing', 2019 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2019 ,Hsinchu. [MOST 106-2314-B-309-001]
    Y.-L. Chiang, S.-C. Yen, M.-J. Lee* and W. Lee* ,'Enhancement of detection sensitivity in quantitative protein assay based on dye-doped liquid crystal', 2018 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2018 ,Taipei, Taiwan.
    C.-M. Lin, W.-G. Wu, P.-C. Wu, M.-J. Lee* and W. Lee* ,'Dielectric biosensor for label-free protein detection with dual-frequency liquid crystal', 2018 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2018 ,Taipei, Taiwan.
    F.-F. Duan, P.-C. Wu, M.-J. Lee* and W. Lee* ,'Detection of the cancer biomarker CA125 probed by a nematic film on a single glass substrate', 2018 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2018 ,Taipei, Taiwan. [MOST 106-2314-B-309-001]
    W.-L. Hsu, P.-C. Wu, M.-J. Lee* and W. Lee* ,'Unsandwiched liquid crystal for bioassay of proteins and DNA', 2018 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2018 ,Taipei, Taiwan. [MOST 106-2314-B-309-001]
    A. Karn, Y.-C. Lin, P.-C. Wu, M.-J. Lee, and W. Lee* ,'Quantitative biosensing using dye liquid crystal', 2017 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2017 , pp. 184–186 ,Taichung, Taiwan.
    C.-M. Lin, P.-C. Wu, M.-J. Lee, and W. Lee* ,'Dual-frequency liquid crystal as a sensing element for protein detection and quantitation [TLCS Outstanding Poster Award]', 2017 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2017 , pp. 195–197 ,Taichung, Taiwan.
    Y.-L. Chiang, M.-J. Lee, and W. Lee* ,'A biosensor based on dye-doped liquid crystals and polarized light', 2017 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2017 , pp. 198–201 ,Taichung, Taiwan.
    M.-J. Lee,* H.-W. Su, C.-H. Lin, Y.-C. Hsiao, Y.-C. Sung and Wei Lee ,'Quantitative liquid crystal-based biosensing techniques for sensitive and label-free detection of biomolecules', 2017 BME Annual Symposium , Nov. 2017 , pp. 29 ,Taoyuan, Taiwan. [MOST 106-2314-B-309-001]
    Chen, Y.-T., P.-C. Wu, M.-J. Lee and W. Lee* ,'Rapid and quantitative biosensing technique based on a dye-LC', 2015 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2015 ,National Central University ,Taoyuan.
    Lin, C.-H., M.-J. Lee and W. Lee* ,'Quantitative protein detection based on electrical responses of liquid crystals', 2015 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2015 ,National Central University ,Taoyuan.
    Chang, C.-H., Y.-C. Hsiao, M.-J. Lee and W. Lee* ,'Blue phase biosensing of bovine serum albumin', 2015 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2015 ,National Central University ,Taoyuan.
    Sung, Y.-C., Y.-C. Hsiao, M.-J. Lee and W. Lee* ,'Application of cholesteric liquid crystals to biosensing ', 2015 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2015 ,National Central University ,Taoyuan.
    S.-H. Sun, Y.-H. Lee, Y.-C. Sung, M.-J. Lee, and W. Lee* ,'Label-free immunosensor based on a large-birefringence nematic liquid-crystal mixture', 2014 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2014 ,National Chiao Tung University, Hsinchu. [MOST 101-2314-B-309-001-MY3]
    H.-W. Su, C.-H. Lin, M.-J. Lee, and W. Lee* ,'Surface modification of alignment layer by ultraviolet light to promote sensitivity in liquid-crystal-based immunoassay for the cancer biomarker CA125', 2014 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2014 ,National Chiao Tung University, Hsinchu. [MOST 101-2314-B-309-001-MY3]
    Lee, M. J.*, S. Y. Lin, M. H. Sie, G. J. Wang ,'Suppression of polyamine biosynthesis reciprocally regulates osteogenic and adipogenic differentiation of human bone marrow-derived mesenchymal stem cells', Annual Meeting of Orthopaedic Association ROC , Oct. 2014 ,Taipei, Taiwan. [MOST 101-2314-B-309-001-MY3]
    Lin, I. J, Y. J. Huang, Y. P. Huang and M. J. Lee*. ,'Delivery of small interfering RNAs by polyethyleneimine-functionalized carbon nanotubes', 2013 BEST Conference on Biotechnology and Bioengineering , Jun. 2013 ,Yunlin, Taiwan.
    Kuo, J. L., Y. Chen* and M. J. Lee* ,'Effect of low-serum culture on the growth of transformed baby hamster kidney cells ', 2013 BEST Conference on Biotechnology and Bioengineering , Jun. 2013 ,Yunlin, Taiwan.
    H.-W. Su, M.-J. Lee, and W. Lee ,'Ultrahigh sensitivity in liquid-crystal-based immunoassyas by means of ultraviolet surface modification [TLCS Outstanding Student Paper Award]', 2013 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2013 , pp. 52 ,Changhua, Taiwan. [NSC101-2314-B-309-001-MY3]
    S.-H. Sun, M.-J. Lee, Y.-H. Lee, and W. Lee ,'Pushing the limit of liquid-crystal-based immunodetection with a highly birefringent nematic mixture', 2013 Annual Meeting of Taiwan Liquid Crystal Society , Dec. 2013 , pp. 55 ,Changhua, Taiwan. [NSC101-2314-B-309-001-MY3]
    Lee, M. J.*, L. H. Chiang and G. J. Wang ,'Exogenous polyamines promote osteogenic differentiation by reciprocally regulating osteogenic and adipogenic gene expression', Annual Meeting of Orthopaedic Association ROC , Oct. 2012 ,Taipei, Taiwan. [NSC 101-2314-B-309-001-MY3]
    Lin, Y. J., Y. P. Huang, M. J. Lee* ,'Development of polyethyleneimine- functionalized multiwalled carbon nanotube as gene delivery reagent', Annual Meeting of the Polymer Society , Jan. 2012 ,Chung Li, Taiwan.
    Lee, M. J.* ,'Effect of polyamines on the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells', Sixth Annual Meeting of Taiwan Society for Stem Cell Research (TSSCR), , October 9, 2010. , Oct. 2010 ,Taichung, Taiwan (Plenary speaker).
    Lee, M. J., C. M. Huang, H. T. Chen, G. J. Wang, M. L. Ho, and J. K. Chang ,'Suppression of PPARγ induces osteogenic gene expression and differentiation of adipose tissue-derived stem cells', Annual Meeting of Orthopaedic Association ROC , Oct. 2008 ,Taoyuan, Taiwan (Oral presentation).
    Lee, M. J., H. T. Chen, M. L. Ho, Y. H. Chen, H. I. Wang, G. J. Wang, and J. K. Chang ,'Osteogenic potentials of adipose tissue-derived stem cells: An in vivo study', Annual Meeting of Orthopaedic Association ROC , Oct. 2008 ,Taoyuan, Taiwan.
    Chang, J. K., H. T. Chen, C. M. Huang, M. J. Lee, G. J. Wang, and M. L. Ho ,'Enhancement of osteogenesis through interfering PPARγ2 mRNA in 3T3-L1 cell line', Annual Meeting of Orthopaedic Association ROC , Oct. 2007 ,Taoyuan, Taiwan.
    Lee, M. J., W. Lin, R. Lo, R. R. Yang and H. Huang ,'Characterization of wild-type and mutant spermidine synthases from Escherichia coli', The 21st Joint Annual Conference of Biomedical Sciences , Mar. 2006 , 231 ,.
    Lee, M. J., C. Y. Huang, I. Z. Sam and H. Huang ,'Molecular cloning and functional characterization of HP0832 gene from Helicobacter pylori', The Nineteenth Joint Annual Conference of Biomedical Sciences , Apr. 2004 , 327 ,.
    Lee, M. J. and I. M. Chu ,'Study on the air/water interfacial adsorption of an egg phosphatidylcholine and Tween 80 mixture', The Fifth Conference on Biomedical Engineering , Dec. 2000 , 595 ,.


     專利 Patent
    專利名稱
    Patent name
    狀態
    Status
    類別
    Category
    公告年月
    Date of announcement
    液晶感測器及用於檢測生物分子的方法 獲證 發明 2015/05

     研究計畫 Research project
    計畫日期
    Project date
    計畫分類
    Project category
    計畫名稱
    Project title
    擔任職位
    Position of employment
    2021/8 ~ 2022/7 學術研究計畫(個人型) 開發以溶致型液晶為感測媒介之高靈敏度無標記DNA適體電化學生物感測器以突破現有技術無法於液晶-玻璃界面進行即時偵測的限制 主持人
    2020/8 ~ 2021/7 學術研究計畫(個人型) 開發以溶致型液晶為感測媒介之高靈敏度無標記DNA適體電化學生物感測器以應用於人類血清癌症生物標記之即時偵測 主持人
    2020/8 ~ 2021/7 學術研究計畫(校內補助) 探討大黃萃取物中抗發炎成分之疼痛抑制功效及其對成骨作用的影響 主持人
    2019/8 ~ 2020/7 產學合作計畫 探討以DNA適體篩選之骨硬化蛋白抑制劑之成骨作用機制以應用於骨質疏鬆症新藥研發 共同/協同主持人
    2017/8 ~ 2018/10 學術研究計畫(個人型) 利用DNA適體開發小分子藥物篩選平台以用於骨質疏鬆症新藥研發(2/2) 主持人
    2017/8 ~ 2018/10 學術研究計畫(個人型) 開發高靈敏度與可精準量化之無標記液晶免疫偵測技術以應用於血清癌症生物標記之檢測 主持人
    2016/8 ~ 2017/7 學術研究計畫(個人型) 利用DNA適體開發小分子藥物篩選平台以用於骨質疏鬆症新藥研發(1/2) 主持人
    2016/1 ~ 2016/12 學術研究計畫(校內補助) 開發高靈敏度與可精準量化之無標記液晶免疫偵測技術以應用於癌症生物標記之檢測 主持人
    2015/1 ~ 2015/12 產學合作計畫 利用DNA適體/氧化石墨烯奈米複合材料作為小干擾RNA轉殖載體以開發乳癌標靶治療技術 共同/協同主持人
    2014/10 ~ 2015/9 學術研究計畫(個人型) 以聚乙烯亞胺官能化氧化石墨烯作為製備誘導性多能幹細胞之非整合性非病毒型基因轉殖載體 主持人
    2014/1 ~ 2014/12 產學合作計畫 抗癌藥物Endoxan造成乳癌細胞轉移機制之探討 共同/協同主持人
    2014/1 ~ 2014/12 產學合作計畫 探討褪黑激素在卵巢癌治療策略及其分子機轉 主持人
    2013/1 ~ 2013/12 產學合作計畫 探討趨化激素受體CXCR4與抗癌藥物Endoxan造成乳癌細胞轉移之關聯性 共同/協同主持人
    2013/1 ~ 2013/12 產學合作計畫 以聚乙烯亞胺官能化之多壁奈米碳管作為基因轉殖載體 共同/協同主持人
    2012/8 ~ 2015/7 學術研究計畫(個人型) 利用多元胺類化合物之促骨生成效用提升骨質疏鬆動物模式之骨質新生 主持人
    2011/12 ~ 2012/7 學術研究計畫(個人型) 以多元胺的促骨生成效用改善抗癌藥物所引起之骨質疏鬆 主持人
    2011/9 ~ 2012/8 課程改進與教學型計畫 100學年度長榮大學申請教育部補助辦理跨領域學分學程 非計畫主持人:計畫撰寫及聯絡人
    2009/11 ~ 2010/7 學術研究計畫(個人型) 提升CXCR4之表現以增加幹細胞之造骨功能 主持人


     推廣教育 Extension education
    期間
    Period
    教育班別
    Education class category
    課程名稱
    Course title
    修課人數
    Number of students
    2012/02 ~ 2012/06 隨班附讀學士學分班 有機化學 1
    2012/02 ~ 2012/06 隨班附讀學士學分班 生物化學實驗II 1
    2012/02 ~ 2012/06 隨班附讀學士學分班 生物化學II 1
    2011/09 ~ 2012/01 隨班附讀學士學分班 生物化學I 1
    2011/09 ~ 2012/01 隨班附讀學士學分班 生物化學實驗I 1
    2011/09 ~ 2012/01 生物科技學系學士學分班 分析化學 1
    2011/09 ~ 2012/01 生物科技學系學士學分班 分析化學實驗 1
    2011/02 ~ 2011/06 生物科技學系學士學分班 有機化學 1
    2011/02 ~ 2011/06 生物科技學系學士學分班 有機化學實驗 1
    2010/09 ~ 2011/01 生物科技學系學士學分班 勞務教育 1
    2010/09 ~ 2011/01 生物科技學系學士學分班 普通生物學I 1

     其他機構專業服務 Professional service at other organization
    起迄年月
    Period
    服務單位
    Department
    職稱
    Position
    2021/04 ~ 2021/04 國立陽明交通大學 109學年度第二學期光電學院碩士班碩士學位考試委員
    2021/02 ~ 2021/02 國立陽明交通大學 109學年度第二學期光電學院碩士班碩士學位考試委員
    2020/09 ~ 2020/09 國立交通大學 109學年度第一學期光電學院碩士班碩士學位考試委員
    2020/08 ~ 2020/08 國立交通大學 109學年度第一學期光電學院碩士班碩士學位考試委員
    2020/07 ~ 2020/07 嘉南藥理大學 教師著作升等審查委員
    2020/04 ~ 2020/04 高雄市立小港高級中學 108學年度模擬面試活動委員
    2020/11 ~ 2020/11 高雄市立文山高級中學 109學年度學群探索講座
    2020/10 ~ 2020/10 慈濟科技大學 教師著作升等審查委員
    2020/01 ~ 2020/01 國立交通大學 108學年度第一學期光電學院碩士班碩士學位考試委員
    2019/04 ~ 2019/04 屏東縣私立美和高中 申請入學模擬面試委員
    2017/03 ~ 2017/03 國立新化高級中學 大學甄試模擬面試講師
    2016/09 ~ 2016/09 國立交通大學 104學年度第二學期光電學院碩士班碩士學位考試委員
    2016/03 ~ 2016/03 正義高中 大學甄試模擬面試講師
    2016/02 ~ 2016/02 國立交通大學 104學年度第二學期光電學院碩士班碩士學位考試委員
    2014/07 ~ 2014/07 國立交通大學 102學年度第二學期光電學院碩士班碩士學位考試委員
    2014/06 ~ 2014/06 南寧高中 營隊授課教師
    2014/06 ~ 2014/06 國立交通大學 102學年度第二學期光電學院碩士班碩士學位考試委員
    2014/03 ~ 2014/03 國立清華大學生物科技研究所 102學年度第二學期博士學位考試委員會論文口試委員
    2014/11 ~ 2014/11 樹人醫專 教師著作升等審查委員
    2013/03 ~ 2013/03 台糖公司 101年度具碩士學位人員初任專業性職位甄試評審委員
    2012/06 ~ 2012/06 國立清華大學生物科技研究所 100學年度第二學期碩士學位考試委員會論文口試委員
    2012/04 ~ 2012/04 國立岡山高級中學 大學模擬面試委員
    2011/10 ~ 2011/10 國立清華大學生物科技研究所 100學年度第一學期碩士學位考試委員會論文口試委員
    2010/01 ~ 2010/01 國立清華大學生物科技研究所 98學年度第一學期碩士學位考試委員會論文口試委員
    2000/08 ~ 2001/07 台灣神隆股份有限公司 研發部助理研究員

     獎勵及指導學生獲獎 Rewards and awards won by student advisee
    獲獎日期
    Date of award
    獲獎名稱
    Award title
    授獎單位
    Organization conferring the award
    2014/06/02 101學年度教學優良獎 長榮大學
    2012/12/01 100學年度健康科學學院績優導師 長榮大學健康科學學院
    2012/11/14 100學年度校績優導師 長榮大學

     校內外演講 On-campus and off-campus speeches
    演講日期
    Date of speech
    演講題目
    Title of speech
    邀請單位
    Inviting organization
    2020/11/04 Innovative Technologies of Liquid Crystal-Based Biosensors 元智大學化學工程與材料科學學系
    2019/09/25 Bone Regenerative Medicine and New Drug Development 國立高雄大學生命科學系
    2012/11/01 Exogenous Polyamines Promote Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells College of Health Sciences, Chang Jung Christian University, Tainan, Taiwan
    2009/10/23 Application of stem cells and regenerative medicine in skeletal diseases Department of Chemical Engineering, National Cheng Kung University, Tainan, Taiwan
    2008/03/30 Identification and Characterization of Physiologically Significant Proteins from Helicobacter pylori Institute of Marine Biology, National Sun Yat-sen University, Kaohsiung, Taiwan
    2008/10/09 Application of adipose tissue-derived stem cells (ADSCs) in cell therapy of osteoporosis College of Health Sciences, Chang Jung Christian University, Tainan, Taiwan

     指導學生論文 Thesis advisor
    年度
    Year
    姓名
    Name
    學位
    Degree
    論文名稱
    Thesis title
    共同指導教授
    Thesis co-advisor
    2020 顏世淳 碩士 液晶與高分子前驅物複合材料生物感測器 李偉
    2019 段飛帆 碩士 以高分子穩定型液晶膜做為癌症生物標誌CA125之無標記免疫檢測手段 李偉
    2018 白兆平 碩士 單基板液晶薄膜的蛋白質生物傳感及免疫檢測技術 李偉
    2018 江宜倫 碩士 利用染料摻雜液晶搭配線偏振光作為蛋白質與免疫複合體之生醫檢測 李偉
    2018 林靖旻 碩士 雙頻液晶之介電分析應用於無標記蛋白質的量化檢測 李偉
    2016 林琪皓 碩士 以光電法與電容法發展液晶生物檢測的定量分析 李偉
    2016 宋淯謙 碩士 光學紋理觀測之外的液晶生醫檢測技術:垂直錨定膽固醇液晶生醫感測器開發 李偉
    2014 蘇慧汶 碩士 開發高靈敏度之液晶感測器以應用於癌症生物標記CA-125之無標記免疫偵測 李偉
    2014 孫士弘 碩士 使用高複折射率液晶以提升癌症生物標記CA125之液晶免疫檢測靈敏度 李偉
    2012 林憶柔 碩士 以聚乙烯亞胺官能化奈米碳管作為小分子干擾RNA傳遞載體

     指導學生參與科技部或其他政府機構專題研究計劃 Student advisee participation in independent research projects of the Ministry of Science and Technology or other
    執行期限
    Project period
    姓名
    Name
    學位
    Degree
    計劃名稱
    Project title
    2017/07/01 ~ 2018/02/28 高明賢 學士 探討降血脂藥物是否透過骨硬化蛋白之抑制以促進成骨分化
    2015/07/01 ~ 2016/02/29 姜柏廷 學士 多元胺生合成抑制劑DFMO在人類骨髓間葉幹細胞成骨分化中對胎球蛋白B(Fetuin B)之調控
    2014/07/01 ~ 2015/02/28 林欣穎 學士 探討鈣離子傳輸與多元胺促骨生成作用之關聯
    2012/07/01 ~ 2013/02/28 林彥丞 學士 以聚乙烯亞胺官能化之多壁奈米碳管作為基因轉殖載體
    2010/07/01 ~ 2011/02/28 陳智源 學士 多元胺對骨髓間葉幹細胞骨分化相關基因BMP-2之影響


     指導學生畢業專題 Graduation thesis of student advisee
    執行期間
    Implementation period
    題目
    Title
    學生姓名
    Student name
    2018/07/01 ~ 2020/01/31 探討黃岑素與茜素於人類成骨細胞之促骨生成作用機制 謝承恩
    2018/07/01 ~ 2020/01/31 探討黃岑素與茜素於人類成骨細胞之促骨生成作用機制 黃筠珈
    2018/07/01 ~ 2020/01/31 探討聚乙烯亞胺官能化氧化石墨烯於人類乳癌細胞的質體DNA轉殖效率 林庭妤
    2018/07/01 ~ 2020/01/31 探討聚乙烯亞胺官能化氧化石墨烯於人類乳癌細胞的質體DNA轉殖效率 張雅蓁
    2016/07/01 ~ 2018/01/31 探討聚乙烯亞胺官能化氧化石墨烯與HB5適體之結合及其對人類乳癌細胞存活率的影響 黃品嘉
    2016/07/01 ~ 2018/01/31 探討聚乙烯亞胺官能化氧化石墨烯與HB5適體之結合及其對人類乳癌細胞存活率的影響 曾昱嘉
    2016/07/01 ~ 2018/01/31 探討黃芩素與茜素對小鼠成骨細胞分化的影響 謝昇祐
    2016/07/01 ~ 2018/01/31 探討黃芩素與茜素對小鼠成骨細胞分化的影響 鄭庭卉
    2016/07/01 ~ 2018/01/31 探討atorvastatin對人類成骨細胞成骨分化相關基因表現之影響 洪微雅
    2016/07/01 ~ 2018/01/31 探討atorvastatin對人類成骨細胞成骨分化相關基因表現之影響 劉明豪
    2016/07/01 ~ 2018/01/31 探討降血脂藥物是否透過骨硬化蛋白之抑制以促進成骨分化 高明賢
    2016/07/01 ~ 2018/01/31 利用聚乙烯亞胺官能化氧化石墨烯結合DNA適體及小干擾RNA以開發乳癌標靶治療基因傳遞載體 王意姈
    2015/07/01 ~ 2017/01/31 探討多元胺生合成抑制劑DFMO於人類骨髓間葉幹細胞之促骨生成作用機制 黃新庭
    2015/07/01 ~ 2017/01/31 抗癌藥物Endoxan造成乳癌細胞轉移機制之探討 黃翊雯
    2015/07/01 ~ 2017/01/31 探討多元胺生合成抑制劑DFMO對人類成骨細胞分化之影響 陳雁綺
    2015/07/01 ~ 2017/01/31 探討多元胺代謝抑制劑MDL72527對人類成骨細胞分化之影響 黃文隆
    2014/09/01 ~ 2015/05/31 探討鈣離子傳輸與多元胺促骨生成作用之關聯 林欣穎
    2014/09/01 ~ 2015/05/31 外生性多元胺及其生合成之抑制對細胞內多元胺平衡之影響 謝旻樺
    2014/02/01 ~ 2016/01/31 多元胺生合成抑制劑DFMO在人類骨髓間葉幹細胞成骨分化中對胎球蛋白B(Fetuin B)之調控 姜柏廷
    2014/02/01 ~ 2016/01/31 利用DNA適體結合聚乙烯亞胺官能化氧化石墨烯以開發乳癌標靶治療基因傳遞載體 鍾采妍
    2014/02/01 ~ 2016/01/31 以聚乙烯亞胺官能化氧化石墨烯轉殖siRNA干擾乳癌細胞蛋白質表現 王婉媃
    2014/02/01 ~ 2016/01/31 探討多元胺生合成之抑制對成骨分化與多元胺代謝相關蛋白質表現之影響 卓淇祥
    2013/09/01 ~ 2014/05/31 以聚乙烯亞胺官能化之氧化石墨烯作為小分子干擾RNA傳遞載體 黃宇婕
    2013/09/01 ~ 2014/05/31 探討趨化激素受體CXCR4與抗癌藥物Endoxan造成乳癌細胞轉移之關聯性 陳姿宇
    2013/09/01 ~ 2014/05/31 探討蘿蔔硫素抑制卵巢癌細胞增生與造成細胞凋亡之機轉與細胞週期作用機轉 楊韻茹
    2012/09/01 ~ 2013/05/31 以聚乙烯亞胺官能化之多壁奈米碳管作為基因傳遞載體 林彥丞
    2012/09/01 ~ 2013/05/31 胍戊胺對人類骨髓間葉幹細胞成骨分化的影響 林冠良
    2012/09/01 ~ 2013/05/31 多元胺生合成路徑之抑制對人類骨髓間葉幹細胞成骨分化的影響 蔡有翔
    2012/09/01 ~ 2013/05/31 奈米銀纖維材料之抗菌測試 張雅嵐
    2012/09/01 ~ 2013/05/31 屍胺對人類骨髓間葉幹細胞成骨分化的影響 黃聖桓
    2011/09/01 ~ 2012/05/31 以多元胺回復抗癌藥物環磷酰胺(Endoxan)於人類骨髓間葉幹細胞中所造成的成骨分化抑制 姜嵐馨
    2011/09/01 ~ 2012/05/31 多元胺生合成路徑之抑制對人類骨髓間葉幹細胞成骨分化的影響 林俊佑
    2011/09/01 ~ 2012/05/31 抗癌藥物Endoxan對乳癌細胞中趨化激素受體CXCR4的基因與蛋白質表現之影響 林彥旭
    2010/09/01 ~ 2011/05/31 多元胺對人類骨髓間葉幹細胞骨分化相關基因 BMP2 之影響 陳智源
    2010/09/01 ~ 2011/05/31 開發含多元胺成分之幹細胞培養基以誘導成骨分化 許家睿
    2010/09/01 ~ 2011/05/31 PEI官能化之奈米碳管對HeLa-S3細胞存活率之影響 汪柔均
    2010/09/01 ~ 2011/05/31 多元胺於小鼠骨母前驅細胞促骨生成能力探討 王玉菁
    2010/09/01 ~ 2011/05/31 探討多元胺對骨髓幹細胞的骨分化效果 林佳侖
    2010/09/01 ~ 2011/05/31 PEI官能化之奈米碳管對HeLa-S3細胞存活率之影響 李怡萱

     指導學生校外實習 Student advisee off-campus internship
    學年/學期
    Academic year/semester
    學生姓名
    Student name
    學生系級
    Student department and class
    實習機構
    Organization of internship
    108 / 2 王詩涵 大學部 生科系 2 年 A 班 國立成功大學醫學院細胞生物與解剖學研究所
    107 / 2 黃筠珈 大學部 生科系 3 年 A 班 國立成功大學醫學院細胞生物與解剖學研究所
    107 / 2 林庭妤 大學部 生科系 3 年 A 班 國立成功大學醫學院細胞生物與解剖學研究所
    107 / 2 謝承恩 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    106 / 2 曾昱嘉 大學部 生科系 3 年 A 班 高雄醫學大學生物醫學暨環境生物學系
    106 / 2 黃品嘉 大學部 生科系 3 年 A 班 國立成功大學醫學院細胞生物與解剖學研究所
    106 / 2 鄭庭卉 大學部 生科系 3 年 A 班 長榮大學生物科技學系
    105 / 2 劉家宏 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    105 / 2 王意姈 大學部 生科系 3 年 A 班 高雄醫學大學生物醫學暨環境生物學系
    105 / 2 高明賢 大學部 生科系 3 年 A 班 國立成功大學醫學院細胞生物與解剖學研究所
    105 / 2 洪微雅 大學部 生科系 3 年 A 班 高雄醫學大學香粧品學系
    104 / 2 黃新庭 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    104 / 2 黃文隆 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    104 / 2 陳雁綺 大學部 生科系 3 年 A 班 高雄醫學大學生物醫學暨環境生物學系
    104 / 2 黃翊雯 大學部 生科系 3 年 A 班 高雄醫學大學生物醫學暨環境生物學系
    103 / 2 卓淇祥 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    103 / 2 姜柏廷 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    103 / 2 鍾采妍 大學部 生科系 3 年 A 班 國立交通大學影像與生醫光電研究所
    102 / 2 林欣穎 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    102 / 2 謝旻樺 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    101 / 2 黃宇婕 大學部 生科系 3 年 A 班 國立交通大學影像與生醫光電研究所
    101 / 2 陳建學 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    100 / 2 林彥丞 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    100 / 2 林冠良 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    100 / 2 蔡有翔 大學部 生科系 3 年 A 班 高雄醫學大學生物醫學暨環境生物學系
    100 / 2 黃聖桓 大學部 生科系 3 年 A 班 高雄醫學大學生物醫學暨環境生物學系
    100 / 2 林彥旭 大學部 生科系 3 年 A 班 國立清華大學生命科學系
    099 / 2 劉佩禎 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    099 / 2 林雅莙 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    099 / 2 林俊佑 大學部 生科系 3 年 A 班 國立成功大學附設醫院骨科
    099 / 2 廖建泓 大學部 生科系 3 年 A 班 國立成功大學附設醫院骨科
    099 / 2 姜嵐馨 大學部 生科系 3 年 A 班 國立成功大學附設醫院骨科
    098 / 2 陳智源 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    098 / 2 廖冠宇 大學部 生科系 3 年 A 班 高雄醫學大學骨科學研究中心
    098 / 2 王玉菁 大學部 生科系 3 年 A 班 國立清華大學生命科學系
    098 / 2 汪柔均 大學部 生科系 3 年 A 班 國立清華大學生命科學系

    長榮大學 深耕在地,連結國際,成為社會責任領航大學

    71101 台南市歸仁區長大路1號  (06) 2785123
    No.1,Changda Rd.,Gueiren District, Tainan City 71101, Taiwan(R.O.C.)


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