專長	Specialties
營養與發炎	Nutrition and inflammation
營養生化	Nutritional biochemistry
保健食品與發炎

畢/肄業學校 School of graduation/non-completion	主修學門系所 Department of major	學位 Degree	起迄年月 Period
中山醫學大學	營養學系	博士	2006/06 ～ 2013/09
中山醫學大學	營養學系	碩士	2004/06 ～ 2006/09
靜宜大學	食品營養學系	學士	2000/09 ～ 2004/06

服務單位 Service Unit	職稱 Position	起迄年月 Period
健康科學學院	執行秘書	2019/08 ～ 迄今
職涯發展及校友中心	執行秘書	2018/08 ～ 2019/08

服務學校 Service School	服務單位 Service Unit	職稱 Position	起迄年月 Period
中山醫學大學	乳房外科	博士後研究員	2016/08 ～ 2017/07
中國醫藥大學	營養學系	博士後研究員	2013/08 ～ 2015/07

Lin, H. C.; Su, S. L.; Lu, C. Y.; Lin, A. H.; Lin, W. C.; Liu, C. S.; Yang, Y. C.; Wang H. M.; Lii, C. K.; Chen, H. W. , 'Andrographolide inhibits hypoxia-induced HIF-1α-driven endothelin 1 secretion by activating Nrf2/HO-1 and promoting the expression of prolyl hydroxylases 2/3 in human endothelial cells,' Environ Toxicol., Vol.32, No.3, Jun. 2017, pp918-930. (SCI )

Liu, K. L.; Yang, Y.C.; Yao, H. T,; Chia, T, W.; Lu, C. Y.; Li, C. C.; Tsai, H. J.; Lii, C. K.; Chen, H. W. , 'Docosahexaenoic acid inhibits inflammation via free fatty acid receptor FFA4, disruption of TAB2 interaction with TAK1/TAB1 and downregulation of ERK-dependent Egr-1 expression in EA.hy926 cells. ,' Mol Nutr Food Res., Vol. 60, No. 2, Dec. 2016, 430-443. (SCI )

Lu, C. Y.; Yang, Y. C.; Li, C. C.; Liu, K. L.; Lii, C. K.; Chen, H. W., 'Andrographolide inhibits TNFα-induced ICAM-1 expression via suppression of NADPH oxidase activation and induction of HO-1 and GCLM expression through the PI3K/Akt/Nrf2 and PI3K/Akt/AP-1 pathways in human endothelial cells.,' Biochem Pharmacol., Vol. 91, No. 1, Sep. 2014, 40-50. (SCI ) [NSC 100-2313-B-039-002-MY3]

Chao, C. Y.; Lii, C. K.; Ye, S. Y.; Li. C. C.; Lu, C. Y.; Lin, A. H.; Liu, K. L.; Chen, H. W. , 'Docosahexaenoic acid inhibits vascular endothelial growth factor (VEGF)-induced cell migration via the GPR120/PP2A/ERK1/2/eNOS signaling pathway in human umbilical vein endothelial cells.,' J Agric Food Chem, Vol. 62, No. 18, May. 2014, 4152-4158. (SCI ) [NSC 101-2313-B-039-007-MY3]

Chao CY, Lii CK, Hsu YT, Lu CY, Liu KL, Li CC, Chen HW., 'Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by andrographolide in MCF-7 human breast cancer cells,' Carcinogenesis, 3, 48, Aug. 2013, 1843-1851. (SCI )

Yang YC, Lii CK, Wei YL, Li CC, Lu CY, Liu KL, Chen HW., ' Docosahexaenoic acid inhibition of inflammation is partially via cross-talk between Nrf2/heme oxygenase 1 and IKK/NF-κB pathways,' J Nutr Biochem ., 24, 1, Jun. 2013, 204-212. (SCI )

Chen HW, Chao CY, Lin LL, Lu CY, Liu KL, Lii CK, Li CC., 'Inhibition of matrix metalloproteinase-9 expression by docosahexaenoic acid mediated by heme oxygenase 1 in 12-O-tetradecanoylphorbol-13-acetate-induced MCF-7 human breast cancer cells,' Arch Toxicol ., 87, 5, May. 2013, 857-869. (SCI )

Lu, C. Y.; Li, C. C.; Lii, C. K.; Yao, H. T.; Liu, K. L.; Tsai, C. W.; Chen, H. W., 'Andrographolide-induced pi class of glutathione S-transferase gene expression via PI3K/Akt pathway in rat primary hepatocytes.,' Food Chem Toxicol., Vol. 49, No. 1, Jan. 2011, 281-289. (SCI ) [NSC 97-2320-B-039-047-MY3]

Yu AL, Lu CY, Wang TS, Tsai CW, Liu KL, Cheng YP, Chang HC, Lii CK, Chen HW., 'Induction of heme oxygenase 1 and inhibition of tumor necrosis factor alpha-induced intercellular adhesion molecule expression by andrographolide in EA.hy926 cells,' J Agric Food Chem, 58, 13, Jul. 2010, 7641-7648. (SCI )

Lu, C.Y.; Li, C. C.; Liu, K. L.; Tsai, C. W.; Lii, C. K.; Chen, H. W. , 'Docosahexaenoic acid down-regulates phenobarbital-induced cytochrome P450 2B1 gene expression in rat primary hepatocytes via the sphingomyelinase/ceramide pathway. ,' J. Nutr. Biochem, Vol. 21, No. 4, Apr. 2010, 338-344. (SCI ) [NSC 95-2320-B-040-029-MY2.]

Chia-Yang Lu, Kai-li Liu and Haw-Wen Chen. ,'Andrographolide suppresses TNF-α-induced ICAM-1 expression via modulation of cellular antioxidant capacity in EA.hy926 cells.', International Conference on Food Factors. , Nov. 2011 , pp.1-281 ,Taiwan.

Chia-Yang Lu, Kai-li Liu and Haw-Wen Chen. ,'Andrographolide Up-regulates Heme oxygenase 1 expression via PI3K/Akt Pathway in human endothelial cells.', Asian Congress of Nutrition , Jul. 2011 , pp.183-184 ,新加坡.

Chia-Yang Lu, Kai-li Liu and Haw-Wen Chen. ,'Andrographolide-Induced Pi Class of Glutathione S-transferase Expression Via PI3K/Akt pathway in Rat Primary Hepatocytes.', International Conference of American Chemical Society , Mar. 2010 ,USA.

Chia-Yang Lu, Chien-Chun Li and Haw-Wen Chen. ,'Mechanism by which DHA down-regulates Phenobarbital-induced Cytochrome P450 2B1 repression in rat primary hepatocytes.', Asian Congress of Nutrition. , Sep. 2007 , p.231 ,Taiwan.

Chia-Yang Lu, Kai-li Liu and Haw-Wen Chen. ,'Andrographolide suppresses TNF-α-induced Oxidative Stress by Modulating Cellular Antioxidation in human endothelial cells.', 第38屆營養年會暨學術研討會 , May. 2012 , pp.120 ,台灣.

Chia-Yang Lu, Kai-li Liu and Haw-Wen Chen. ,'Andrographolide Up-regulates Heme oxygenase 1 expression via PI3K/Akt Pathway in EA.hy926 cells.', 第37屆營養年會暨學術研討會 , May. 2011 , pp.110 ,台灣.

Chia-Yang Lu, Kai-li Liu and Haw-Wen Chen. ,'Andrographolide-induced pi class of glutathione S-transferase gene expression via PI3K/Akt pathway in rat primary hepatocytes.', 第36屆營養年會暨學術研討會 , May. 2010 ,台灣.

計畫日期 Project date	計畫分類 Project category	計畫名稱 Project title	擔任職位 Position of employment	計畫編號 Project number	補助單位 Funding organization
2020/9 ~ 2020/12	學術研究計畫(整合型)	職能養成-團體膳食管理實驗	主持人	109B5206	僅教育部
2020/7 ~ 2020/10	產學合作計畫	(A) 萌芽計畫-風味發酵茶飲開發計畫	主持人	109C330202	僅本校
2020/3 ~ 2020/6	其他計畫	109產業實務融入課程補助計畫-學校午餐實務	主持人		僅本校
2019/8 ~ 2020/7	產學合作計畫	培育氣候變遷對健康影響與調適之營養照護能力計畫	主持人		僅教育部
2019/3 ~ 2019/6	產學合作計畫	108年度第1期產業實務融入課程補助	主持人	E 2-2-5	其他：108年高教深耕計畫-學校自籌款

演講日期 Date of speech	演講題目 Title of speech	邀請單位 Inviting organization	備註 Notes
2020/10/30	從營養研究到食品開發 窺探精釀世界的奧妙	中山醫學大學 營養學系

證照名稱 License name	發證單位 Issuing agency	證照編號 License number	發證年月 Date of issue
食品技師	考試院	專高食技字第000003號	2018/08
保健食品專業人才能力鑑定證書	工業技術研究所與食品工業發展研究所	H-A-04-02-2013	2018/01
食品安全管制系統基礎訓練合格	中華食品安全管制系統發展協會	食安訓字第A103011143號	2014/03
食品安全管制系統基礎訓練合格	食品安全管制系統發展協會	食安訓字第A103032215號	2014/01
營養師證書	衛生福利部	營養字第004815號	2007/09